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buildwithfern.comMethylation been discovered on a range of lysine residues in various histones: K4 (using the single-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, K20 in histone H4, K59 within the globular area of histone H4 2 and K26 of histone H1B three Several proteins liable for the methylation of specific residues have been characterized, and lawyers in my area all however certainly one of these contains a SET domain